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The model predicts that initial knock-down of Keap1 by siKEAP1 is counteracted by increasing Nrf2 concentrations, which subsequently upregulate Keap1 and Srxn1 mRNA production (Fig 3C)

Instead, HC induced a reduction of red fluorescence compared to the DMSO condition similar to CCCP, a known mitochondrial membrane disruptor which causes a complete mitochondria depolarization (Figure 7A)

Reported research-use protocols vary by design and route, but commonly cited daily ranges include

Role of NAD (P) H oxidase

Systemic lupus erythematosus in Kuwaiti children: organ system involvement and serological findings