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Despite high upfront costs, economic modeling suggests potential long-term value
Who should not take GLP-1s GLP-1s in all forms are unsuitable for people who: are pregnant or breastfeeding do not meet the eligibility criteria have a family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN2) Medical Perspective Patients with needle phobia, a preference for pill-based routines, or good adherence to oral administration guidelines may be better suited to oral GLP-1 formulations like semaglutide (Rybelsus, Wegovy), which can enhance treatment acceptance and potentially offer strong glycemic or weight control
Glickman, MD, an obesity medicine physician and owner of Revolution Medicine, Health, and Fitness
this peptide resulted in weight loss and had lipid-lowering and glucose-lowering effects in mice with diet-induced obesity, which were superior to the effects seen with a GLP-1 receptor-selective agonist [77]
Its becoming more clear how damaging visceral fat is because it contributes to diabetes, fatty liver disease, kidney disease, and cardiovascular disease
