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We then overexpressed GCLC in cells with ACTL6A knocked down and found that GCLC reversed the inhibition of cell proliferation (Fig

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However, patients may experience these symptoms for various reasons during treatment, including pre-existing diabetic neuropathy, rapid metabolic changes, nutritional deficiencies, or concurrent medications

This well-established approach recognises that the physiological mechanisms behind obesity and T2D are inextricably intertwined, and thus recommends treating obesity not merely as a risk factor but as the primary therapeutic target in T2D