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For ethical reasons, a placebo controlled trial would not be appropriate [36]

For individuals in Texas considering medically supervised weight-loss treatment, consultation with a qualified physician is an essential first step

As body weight decreases, the dose of levothyroxine needed to maintain euthyroidism may also decrease, since thyroid hormone replacement is partially weight-based

CD38 was also considered a major contributor to the acquired resistance to PD1/PDL1 blockade, causing CD8+ T-cell suppression

Preservative-containing medicines, such as certain eye drops, may not be safe to use past the expiration date because the preservatives may no longer be effective against bacterial growth

Therefore, we studied the effect of our nanocarriers on a dietary mouse model of MASLD, the Western diet model, during a daily chronic treatment of 4 weeks