allodynia glp-1 treatment If your skin hurts to touch while on GLP-1, you're not imagining it. A new case series documents as a dose-dependent side effect of medications. Here's what we know so Doctor Shares A Rare Side

These drugs mimic the action of glucagon-like peptide-1, a hormone that enhances insulin secretion, reduces glucagon levels, and slows gastric emptying

doi: 10.1161/JAHA.120.016887 63 CavalcantiABZampieriFGRosaRGAzevedoLCPVeigaVCAvezumAet al

An exploratory analysis of those formerly using insulin in conjunction with GLP-1 receptor agonist (who were originally excluded from the main analysis) showed an increase in HbA1c (1.2%1.3%, P =0.006) (Supplemental Table S1), suggesting that the insulin dose adjustments made after discontinuing GLP-1 receptor agonists were insufficient to maintain glycemic control

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