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Additionally, accumulation of free toxic compounds such as long chain fatty acid surrounding the mitochondria induces mitochondrial membrane permeability because of mitochondrial membrane depolarization and membrane canals formation
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10.1161/CIRCULATIONAHA.122.059595 164
In rat HD models, neuropathological changes in the rat striatum were induced by 3-nitropropionic acid, and L-theanine exhibited neuroprotective effects, which mainly depended on not only inhibiting the production of harmful NO but also preventing the change of neurotransmitters in the striatum (51)
Moreover, few studies consider whether the infants themselves received acetaminophen postnatally, such as for fever or pain relief
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