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THE PRODUCTS DESCRIBED HEREIN ARE FOR RESEARCH USE ONLY

Electrophysiological recordings further supported this, revealing that Dihexa caused a 1.6-fold increase and Nle-AngIV caused a 1.7-fold increase in the frequency of AMPA-mediated mEPSCs compared to vehicle-treated neurons, indicating an expansion of functional synapses without altering individual synapse properties such as amplitude, rise, or decay times

That being said, Dihexa was administered to the rats in doses of 1.44 mg/kg of 2.88 mg/kg in order to see how levels of AngIV changed in response to the nootropic compound

Binding studies employed tritiated small molecule HGF analogs to map the distribution of HGF/c-Met receptors in the brain, establishing a correlation with known AT4 receptor densities

You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc

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