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Improvement of sea fennel ( Crithmum maritimum L.) nutritional value through iodine biofortification in a hydroponic floating system

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Ross DS, Litofsky D, Ain KB, Bigos T, Brierley JD, Cooper DS, Haugen BR, Jonklaas J, Ladenson PW, Magner J, Robbins J, Skarulis MC, Steward DL, Maxon HR, Sherman SI

When cysteine pools drop, glutathione synthesis stalls, the cellular antioxidant buffer collapses, and proteins that depend on disulfide bond formation for foldingincluding every immunoglobulin and every insulin molecule ever producedmisfold and aggregate

Mice were first anesthetized with 5% isoflurane (Panion & BF Biotech), after which they were shaved and depilated

(2021) 8:e2101222