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Participants were evaluated with fluorodeoxyglucose (FDG) positron emission tomography (PET) to assess cerebral glucose metabolism at baseline and at the end of the 2 months study period

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Well, fast forward first week, second week, third week

In the SUSTAIN 6 trial (published in the New England Journal of Medicine, 2016), which examined cardiovascular outcomes in over 3,000 patients with type 2 diabetes at high cardiovascular risk, participants receiving semaglutide demonstrated statistically significant reductions in major adverse cardiovascular events