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But if you suspect a storage issue AND notice reduced effectiveness, the most prudent action is to start with a fresh, properly stored supply and see if your results improve

Understanding this distressing symptom requires a deep clinical dive into esophageal motility, mucosal irritation, and the neuro-muscular reflexes of the upper digestive tract

This 12-year period has been the subject of repeated legislative proposals to shorten it, most recently in the context of the Inflation Reduction Act, but as of early 2026 it remains intact

Notably, significant reductions were observed in CAT total and energy score at 4 weeks and CAT total, cough, and dyspnea scores at 8 weeks of treatment

On average, patients may lose 5-10% of their body weight within this timeframe

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