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and 3, normal strong response

We discuss how these drugs work to promote weight loss, the source of their side effects, and the newer compounds soon to overcome some of those side effects, such as muscle loss

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No ramp-up is used

Such an ideal unimolecular antidiabetic agent should have complementary effects correcting multiple pathophysiological defects of T2D and be safe, durable, well-tolerated, easy to administer, and cost-effective