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This dual effect may make tirzepatide more effective than other injectable diabetes medications

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Abrupt cessation typically triggers rapid appetite return, hunger sensations, and potential weight regain of 3050% within 36 months

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All these adverse events are considered rare, and experts doubt that some are legitimately caused by GLP-1 drugs

Similarly, Section 503B does not allow for compounding of drugs that are essentially a copy of one or more approved drugs but the statute notes that this does not apply to drugs on the drug shortage list in effect under Section 506E. The 506E shortage list recognizes drugs that have low availability due to manufacturing or quality problems, delays or discontinuations