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Results: Prescription type was associated with all four side effects (all p 0.88), indicating that younger patients reported higher frequency of poor appetite and end-of-dose crash, and lower levels of insomnia

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Concurrently, the NOD-like receptor pyrin domain-containing protein 3 (NLRP3) inflammasome acts as a key mediator of innate immune responses and has been increasingly implicated in neuroinflammatory cascades leading to neuronal loss in PD