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In comparison, semaglutide studies showed 15% body weight reduction after 68 weeks

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Tirzepatide stands out for its ability to promote substantial weight loss

Summary: GLP-1 medications do not directly cause muscle loss, but the substantial weight reduction they facilitate results in some lean body mass loss, similar to other weight loss methods

Folate insufficiency may be difficult to detect without a blood test, but not because it is a superfluous nutrient

The STEP 1 trial showed that participants receiving 2.4 mg weekly for 68 weeks lost an average of 14.9% of their body weight compared to 2.4% in the placebo group