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doi: 10.1111/dom.12932
Moreover, GLP-1RA and DPP-4 inhibitors are approved for the treatment of T2DM and exhibit potential pleiotropic effects on the heart and kidneys, which may be independent of or dependent on the hypoglycemic effects
Neither experience is necessarily better
Instead of titrating to the full doses recommended for obesity treatment (e.g., semaglutide 2.4 mg weekly or tirzepatide up to 15 mg), microdosing involves starting and staying at much lower doses sometimes as low as 0.1 to 0.25 mg per week for semaglutide or even intermittent use
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Hormone guidance from a specialized provider when needed can dramatically enhance results
