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Intracellular iron overload leading to DNA damage of lymphocytes and immune dysfunction in thalassemia major patients
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No clinically validated dose exists, as these are clinical practice patterns, not trial-tested protocols
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The cysteine oxidation code Cysteine side chains sample a ladder of oxoforms with distinct kinetics and reversibility: thiolate (CysS ) sulfenic (CysSOH) disulfide (proteinSSprotein or SSG) / sulfenyl-amide, with further over-oxidation to sulfinic (SO 2 H) or sulfonic (SOH) at higher oxidant loads
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