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Residual disability, estimated to affect 6% of neurologic patients, is the most feared outcome of cobalamin deficiency and is likely to persist if still present after 6 to 12 months of treatment

1,25-Dihydroxyvitamin D modulates L-type voltage-gated calcium channels in a subset of neurons in the developing mouse prefrontal cortex

The mechanism involved in riboflavin uptake by colonocytes has been characterized and involves an efficient and specific carriermediated mechanism that is similar to the one described in the small intestine (36, 37)

Contraindications include polycythemia vera, Leber optic neuropathy, and cobalt allergy

When free radical production outpaces the body's antioxidant defenses a state known as oxidative stress cells accumulate damage that affects energy, immunity, skin health, and accelerates biological aging

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