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During inflammation and trauma acrolein is released, causing damage to biomolecules and altering several cellular processes in neurons, including mitochondria functionality

DOI: 10.3390/toxins6020608 18

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IUBMB Life 52:159164 Loeffler DA, Connor JR, Juneau PL, Snyder BS, Kanaley L, DeMaggio AJ, Nguyen H, Brickman CM, LeWitt PA (1995) Transferrin and iron in normal, Alzheimers disease, and Parkinsons disease brain regions