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Christopher Margrey, DVM

SW: Writing review & editing

During these clinical trials, researchers observed substantial weight loss in participants, which paved the way for a second approval

Rapidly worsening eyesight

About one-third of semaglutide users and a similar proportion of tirzepatide users retained their weight loss or even continued to lose weight

Common Adverse Effects According to pharmaceutical research on semaglutide, gastrointestinal effects are most frequent: nausea (20-44% incidence, usually mild-moderate, improves over time), vomiting (9-24% incidence), diarrhea (20-30% incidence), constipation (20-24% incidence), and abdominal pain (8-20% incidence)