Subcutaneous semaglutide, on the other hand, was more frequently used to replace a previous regimen including an insulin (prandial or basal or both), compared with oral semaglutide (10.2% and 4.2% of cases, respectively), but the difference did not reach statistical significance
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Short acting GLP-1 receptor agonists may cause a brief increase in heart rate, while some long-acting GLP-1 receptor agonists may cause a sustained increase in circadian heart rate
Ethics statement The animal study was approved by Animal Experiment and Laboratory Animal Management Committee of Capital Medical University