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As a first step towards development and commercialization outside of mainland China, Hua Medicine completed a phase 1a trial of HM-002-1005 in the United States in 2024

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In a separate study, LY343794, another glucagon/GIP/GLP-1 triple receptor agonist, decreased body weight and improved glycaemic control in obese mice [97]

Distinct regulation of Th17 and Th1 cell differentiation by glutaminase-dependent metabolism