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Consistent with established principles, CL maturation begins before birth, making PMA more physiologically relevant than postnatal age ( versus age to describe CL maturation (Supplementary Figure S3), suggesting future studies should expand sample sizes to validate these maturation dynamics

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To evaluate the live bacterial assay, we replaced wild-type (WT) human GPI in the humanized E

When these complexes are damaged by lipid peroxidation (the oxidative degradation of lipids in the mitochondrial membrane), ATP production grinds to a halt

Acknowledgements This work was supported by the Burroughs Wellcome Fund (BWF) in Pathogenesis of Infectious Disease (PATH award to B.P.C., PATH award to S.H.), the National Institutes of Health (NIH) (R01AI173004 and R01AI179695 to B.P.C