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They also degrade quickly due to temperature shifts

An in Silico guided identification of nAChR agonists from Withania somnifera

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Cell Mol Neurobiol 33(3):347357 Matsuzaki H, Tamatani M, Mitsuda N, Namikawa K, Kiyama H, Miyake SI, Tohyama M (1999) Activation of Akt kinase inhibits apoptosis and changes in Bcl-2 and Bax expression induced by nitric oxide in primary hippocampal neurons

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