Identification of DPP4/CTNNB1/MET as a theranostic signature of thyroid cancer and evaluation of the therapeutic potential of sitagliptin
For example, a team might pair KLOW with data on mitochondrial membrane potential, ATP production, or oxidative stress markers to see whether changes in tissue recovery markers coincide with shifts in cellular energetics
Gao X, Zhang H, Li K, et al
For instance, the MitoSOX Red probe (Invitrogen, Waltham, MA, USA) can be used to measure oxidative stress localized in the mitochondria, whereas the CellROX Green (Invitrogen, Waltham, MA, USA) and Deep Red probes (Invitrogen, Waltham, MA, USA) can be used to detect intracellular ROS
There was a moderate cell polymorphism
These experiments indicated that, in addition to requiring Cys-dependent de novo biosynthesis of GSH for survival (see above), TrxR1/Gsr-null livers require de novo biosynthesis of Cys via transsulfuration, and that they cannot effectively utilize cystine as a hepatic Cys source [107]
