Pharmacol Rep 66:169173 Dungan KM, Povedano ST, Forst T, Gonzlez JGG, Atisso C, Sealls W, Fahrbach JL (2014) Once-weekly dulaglutide versus once-daily liraglutide in metformin-treated patients with type 2 diabetes (AWARD-6): a randomised, open-label, phase 3, non-inferiority trial
SS-31 for mitochondrial neuropathy SS-31 (Elamipretide) targets the inner mitochondrial membrane, stabilizing cardiolipin and improving electron transport chain efficiency
We asked doctors who prescribe GLP-1 medications to break down this trend and explain whether its worth it to consider microdosing a GLP-1 drug
Proc Natl Acad Sci USA 92 : 10281032 Girnita A, Girnita L, Prete Fd F, Bartolazzi A, Larsson O, Axelson M (2004) Cyclolignans as inhibitors of the insulin-like growth factor-1 receptor and malignant cell growth
Slice through the centre of the GLP-1R bundles bound by different agonists, with a 360 y axis rotation around the centre of each receptor bundle
For orforglipron, participants initiated on higher doses and those on rapid titration schemes appeared to have higher discontinuation rates, providing insights into the optimisation process for the phase 3 trials
