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Khan, K., Cook, J., Kannus, P., Maffulli, N

Concise review: two negative feedback loops place mesenchymal stem/stromal cells at the center of early regulators of inflammation

SAM acts as a key methyl donor for most methylation modifications, including the methylation of DNA, RNA, lipids and histones, and also participates in polyamine biosynthesis, which has a function in multiple cellular processes including regulation of chromatin structure, transcription and translation, DNA stabilization, cell growth and proliferation [50]

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