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Conversely, we found little evidence that GLP-1RAs may cause or exacerbate cognitive impairment, which is of importance to patients who may need to take these medications for their currently licensed (and expanding) indications

Priority Review designation is possible given the magnitude of the trial results, which could shorten this timeline to 6 months

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Pemvidutide is another dual agonist of GLP-1R and GCGR that is currently under clinical investigation

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