Data were analyzed by 2-way ANOVA with Bonferronis post test or 2-tailed Students t test, as indicated
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This Ca 2+ influx, along with elevated ATP, results in exocytosis of the plasma membrane docked immediate release pool (IRP) of insulin granules, a sub-pool of the readily releasable pool (RRP) which contains ~15% of available insulin granules (34)
doi: 10.1016/j.phrs.2015.10.008 22 MahapatraMKKaruppasamyMSahooBM
By interrogating glycolytic and mitochondrial ATP production in mammalian synapses, we seek to uncover how the nervous system achieves metabolic plasticity when facing energetic stress.