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Most of it is preclinical cell cultures and animal models with only limited early clinical data for a few compounds

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Findings remain preliminary, and further investigation is required to clarify their roles

Seven different GLP-1 receptor agonists were used, including semaglutide (Ozempic or Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza)

HRT Type and Route: How They Influence GLP-1 Medication Safety Transdermal estradiol patches bypass first-pass hepatic metabolism, reducing lipid and clotting factor changes compared to oral estrogen