In phase 2 trial data published in The New England Journal of Medicine (2023), retatrutide demonstrated substantial weight loss in adults with obesity with some participants losing over 20% of their body weight over approximately 48 weeks
Peptide therapy requires physician evaluation, comprehensive laboratory testing, and ongoing clinical oversight
We discuss the multiagonists currently in clinical trials and the improvement in efficacy each new generation of these drugs bring
I am now back to the weight I was before I had kids
Clinical trials show average weight loss of 1015% of body weight by 6 months of consistent semaglutide use
GLP-1 medications are eliminated through renal pathways, and reduced kidney function affects both drug tolerance and the risk of complications particularly dehydration-related acute kidney injury, which can occur when GI side effects (nausea, vomiting) reduce fluid intake