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When they found them still effective that became the expiry period

The trade-off is extra complexity

The inflammation-modulatory effects of hBMSC treatment included a significant increase in the gene expression of IL-10 and its receptor in ovarian tissues, elevated serum levels of IL-10, IFN-, and tissue inhibitor of metalloproteinase-2, and a decrease in the gene expression of pro-inflammatory markers such as IL-6, IL-1, CCL2, and CD11c in the adipose tissue of PCOS mice [135]

Activation of the NRF2/SLC7A11/GPX4 signaling pathway leads to elevated GSH levels, reduced MDA and ROS accumulation, suppression of neuronal ferroptosis, lipid peroxidation, and amino acid antioxidant dysfunction, ultimately mitigating neuronal injury

These are real findings

doi:10.1016/j.tibtech.2025.09.014