Warning signs requiring medical attention include: Severe or expanding redness, warmth, or swelling at the injection site suggesting infection Persistent hard lumps that don't resolve Severe abdominal pain or persistent vomiting that may indicate pancreatitis (rare but serious) Signs of allergic reaction including widespread rash, difficulty breathing, or facial swelling Symptoms of gallbladder problems (pain in your upper stomach, fever, yellowing of skin or eyes) Symptoms of thyroid tumors (lump or swelling in your neck, hoarseness, trouble swallowing, shortness of breath) Patients should maintain their regular injection schedule regardless of minor injection-site reactions
Labs and video consults not routinely included
Microdosing GLP-1s means starting at significantly lower doses than standard guidelinessometimes as low as 0.05 to 0.1 mg of semaglutide per week, compared to the usual starting dose of 0.25 mg
Injection site matters in two ways
Site selection, rotation rules, and technique are the same
When the same area receives repeated injections, scar tissue and lipodystrophy can develop beneath the skin surface, invisible to the eye but tangible to the touch
