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For advanced cases, carpal tunnel surgery, including traditional and Endoscopic Carpal Tunnel Release, may be necessary to relieve pressure by cutting the carpal tunnel ligament

PPARa, a potent transcriptional regulator of lipid metabolism, has been established to modulate key proteins governing lipid transport, synthesis, and catabolism in liver and adipose tissues [52, 53]

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In November 2023, AstraZeneca and Eccogene signed an exclusive license agreement for ECC5004, an investigational oral once-daily GLP-1RA for treating obesity, type 2 diabetes, and other cardiometabolic conditions

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HYGIENE A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS A61P3/00Drugs for disorders of the metabolism A61P3/08Drugs for disorders of the metabolism for glucose homeostasis A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g