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They are most often found on the face and hands, and they are larger and more defined than freckles

Levy JE, Jin O, Fujiwara Y, Kuo F, Andrews NC

Plasma membrane Ca2+-ATPase isoform 2a is the PMCA of hair bundles

We found that Dihexa-mediated protection requires activation of Akt, TOR, and MEK signaling, as inhibition of any of these targets attenuates Dihexa-mediated protection