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Recent randomized double-blind trials showed that treatment with GLP-1R agonists reduces cardiovascular events, stroke, and nephropathy 8,9
However, berberine also lowers blood sugar by improving insulin sensitivity and inhibiting glucose production in the liver
PRISMA Checklist for the Meta-analysis
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No contraindication is listed in the UK product information for using these medicines concurrently , and co-prescribing can be appropriate when clinically indicated