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GLP-1RAs, including semaglutide, liraglutide, and tirzepatide, are currently FDA approved for the treatment of obesity in patients with a body mass index (BMI) greater than or equal to 30 or a BMI greater than or equal to 27 in the setting of an obesity-related comorbidity, including asthma

High fat-high fructose diet-induced changes in the gut microbiota associated with dyslipidemia in Syrian hamsters

Hauptman et al., 2023) and less opportunity for physical activity and social interaction (Finlay et al., 2022), which may contribute to increased risk for conditions that contribute to cardiovascular disease (e.g., hypertension, diabetes)

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Effects of a novel pentadecapeptide BPC 157 and methylprednisolone in a murine model of inflammatory bowel disease, Gastroenterology 104 , 782