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Cells overexpressing NKX21 can proliferate in serine/glycine-free medium, whereas NKX21 knockdown inhibits invasive capacity ( Studies have revealed that in the most aggressive subtype of castration-resistant prostate cancer (CRPC), downregulation of protein kinase C / (PKC/) upregulates de novo serine synthesis via the mTORC1/ATF4 signaling pathway

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Experimental timeline At 11 months of age (after one month of diet exposure) females and males received daily subcutaneous injections of vehicle (saline) or GE2 as described above (n = 6-7 (vehicle) and n = 6-8 (GE2)

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These methods make reconstitution easier and help you avoid confusion