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GLP-1 agonists like semaglutide and tirzepatide slow gastric emptying by 30-40% as part of their mechanism of action (Nauck et al., Diabetologia, 2011)

Comment: A commenter expressed concern that limiting survey administration to email and text communications may affect representativeness and data quality because patients who have limited internet access may not be included in the survey

The peptide is not approved by the FDA for human use

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The analysis addresses only the narrow chemical question of whether pH incompatibility would cause degradationa claim that the available evidence does not support