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They further revealed that CTGF can trigger the migration of monocytes in OA by enhancing monocyte chemoattractant protein-1 (MCP-1) expression through interaction with integrin av5 (142)

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The peptide Herdegradin, which downregulates EGFR, stimulates mitophagy through the mTORC2/Akt pathway, effectively inhibiting the growth of EGFR-positive cancers, such as PCa, ultimately inducing the death of PCa cells (Katreddy et al., 2018)