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Endogenous glutathione deficiency and impaired antioxidant defense systems have been increasingly recognized as central to the pathogenesis of many diseases, including COVID-19, through their impact on oxidative stress and inflammatory pathways

References Lu, J

For instance, treatment with the NRK-salvage precursor NR in mice, C

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In contrast, other biofluids such as blood, are more convenient specimens for biomarker screening and detecting metabolic dysregulation in circulation