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Novel potential of metformin on valproic acid-induced autism spectrum disorder in rats: involvement of antioxidant defence system

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Via pattern-recognition receptors, these cells sense pathogen- and damage-associated molecular patterns (PAMPs and DAMPs), triggering the production of proinflammatory cytokines (e.g., TNF-, IL-1, IL-6) and chemokines that drive the inflammatory cascade (Kauna et al., 2022)

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