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1,16,17 Folate Defi ciency reduces estrogen levels

Luis A Hernndez-Flores, MD 2

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The TCF7L2 Gene: Your GLP-1 Regulator The TCF7L2 gene is a GLP-1 regulator and its important because it: Directly regulates the production and secretion of GLP-1 Influences how well GLP-1 can stimulate insulin release Its strongly linked to type 2 diabetes risk (the strongest genetic risk factor identified!) When you have certain variants of TCF7L2, your body produces less GLP-1 and responds more weakly to the GLP-1 you do produce

Abdominal Pain and Heartburn Many GLP-1 users notice mild abdominal discomfort or heartburn, particularly after eating