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doi:10.3390/ijms22147692

Ghrelin a stomach-derived hormone that stimulates GH release through the GHS-R1a receptor

& Kaplan, S

Use With Caution in Research Contexts Because Tirzepatide interacts with GLP-1 and GIP receptor pathways involved in appetite regulation, glucose signaling, digestion, and metabolic function, additional caution may be warranted in research models involving significant metabolic, gastrointestinal, pancreatic, or endocrine-related conditions