Stop using that site and contact a healthcare professional, especially if redness spreads, swelling worsens, the area becomes hot, there is drainage, or you develop fever or systemic symptoms
doi: 10.1155/2015/781938 85
In addition to being administered as a drug to cause oxidative stress, MTX has also been used to induce cachexia, anorexia, intestinal mucositis and digestive absorption problem in experimental animal models (Reference Boukhettala, Leblond and Claeyssens34Reference Sinno, Coquerel and Boukhettala36)
Hsc70 inducer treatment substantially inhibits NCOA4-mediated ferritinophagy and ferroptosis, thereby alleviating the liver injury caused by rifampicin (40)
While on the topic of skin, it is impossible not to mention Marine Collagen as a staple of skin health as we age, which has been proven to enhance skin hydration, elevate elastin levels, and promote overall skin immunity
Wu G, Meininger CJ, McNeal CJ, Bazer FW, Rhoads JM