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The US FDA data are noted here for context only and should not be directly extrapolated to retatrutide or other incretin classes without further evidence

This can reduce the appearance of fine lines and wrinkles while making skin firmer and more elastic

Medically reviewed by Missy Zammichieli, DNP, APRN, FNP-BC Updated March 26, 2026 HEAD-TO-HEAD HOW THEY WORK (AND WHY IT MATTERS) Both medications mimic gut hormones that your body produces naturally after eating

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Katie Jones is a registered nurse and certified IV therapy specialist based in Temecula, California

It has the ability to be converted into glucose when required: it is transformed into energy when our muscles require it