Poursistany H, Azar ST, Azar MT, Raeisi S (2024) The current and emerging Klotho-enhancement strategies
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5 Metformin promotes apoptosis of glioma cells Metformin has recently gained attention for its potential antitumor effects, particularly in various cancer types, including glioblastoma (34)
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In clinical practice, she explained, physicians start low and raise the dose gradually in a process called titration, an approach that "balances treatment efficacy with side effects." Sometimes they intentionally keep someone at a lower, submaximal dose rather than pushing to the maximum
On the contrary, an excess is starting to be associated with: the proliferation and onset of cancer, hepatic-renal damage, neurodegenerative diseases, as well as heart and cardiovascular diseases