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Oxidized PAC-quinone imine metabolites have also been shown to form GSH-conjugates which inhibit glutathione reductase (GR): the decreased activity of GR hampers the detoxification and antioxidant capacity of the GSH-GSSG cycle, further aggravating the pro-oxidative status in the cell (Ndlov et al., 2014)
The mitochondrial profile in women with polycystic ovary syndrome: impact of exercise
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Acknowledgements The authors thank Brith Leidvik and Stefan Nordlander for technical and data assistance
This nerve damage reflects a stocking-glove distribution (Figure 1a), which is closely related to the structure and function of the peripheral nervous system (PNS)
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