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In the Phase 3 TRIUMPH-1 trial reported in 2026, patients on the 12 mg dose lost an average of 28.3% of their body weight over 80 weeks, compared with just 2.2% for placebo (Eli Lilly, 2026)

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Today, we are paying close attention as strong evidence shows these medications lower the risk of heart attack, stroke, and death from heart disease even in people without diabetes

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Pleven, S., et al., Screening for diabetic peripheral neuropathy: subjective versus objective measures