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The mitochondrial metallochaperone SCO1 maintains CTR1 at the plasma membrane to preserve copper homeostasis in the murine heart

Zhou QM, Zhang H, Lu YY, Wang XF, Su SB

Animal research has found other compouds capable of combatting doxorubicin cardiotoxicity, including boswellia (Uma Mahesh 2013), onion extract (Alpsoy 2013), the Chinese herb Panax notoginseng (Liu 2008), the ginger phytochemical 6-gingerol (El-Bakly 2012), and a polyphenol-rich extract of the honeybee product propolis (Alyane 2008)

The major obstacles to developing probes that can monitor GSH dynamics include the reaction reversibility and kinetics of the sensing reaction, as well as the high abundance of GSH (110 mM) inside cells

Patients who are on anticoagulants (i.e., blood thinners) will have their dose adjusted under the care of their cardiologist or hematologist

Kalia M