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The exposure to mecasermin in the Polish Study on Increlex is likely reflective of typical exposures for patients who would be treated in the Canadian context

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Ming et al

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Synthetic osteogenic growth peptide promotes differentiation of human bone marrow mesenchymal stem cells to osteoblasts via RhoA/ROCK pathway

On the contrary, the researchers noted significantly reduced mortality in the epithalamin treated group compared to patients treated with basic therapy alone [10]